CTAD Summit 2024

Evaluation of Slingshot TruCytes™ Cell Mimics on the Accellix Automated Flow Cytometry Platform for Cell Therapy Manufacturing QC

James Cwick, Jyothi Jayaram, Amanda Trent
Accellix, Inc., San Jose, CA
CTAD Summit 2024 | December 3-5 | Boston, USA

Introduction – Cell therapy development and manufacturing require robust quality control (QC) systems to ensure accuracy, consistency, and reliability of cell characterization. The Accellix platform is an automated cartridge-based flow cytometer that is designed for rapid sample-to-analysis results for cell therapy QC workflows. This study evaluates the performance of Slingshot Bioscience’s TruCytes controls with Accellix assays. TruCytes biomarker controls (cell mimics) obviate the need for control blood or cell lines expressing markers of interest, offering a potential for reproducible and modular assay controls for cell therapy manufacturing QC applications, testing incoming and in-process cell material, as well as the final release product.

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